What Are Salmon Sperm Injections? Understanding Polynucleotide Skin Regeneration
What Are Salmon Sperm Injections? A Clinician’s Real Experience with Polynucleotide Treatments
Salmon sperm injections are one of the most misunderstood — yet highly effective — regenerative treatments in aesthetic medicine. While the name is attention-grabbing, the science behind the treatment is robust, well-researched, and increasingly sought after by patients looking for natural under-eye rejuvenation.
I’m Dr. Janice Brown, and I’ve been using — and personally having — polynucleotide injections for over five years. I was one of the first clinicians trained in this treatment in Northern Ireland, and in this article I’ll explain what salmon sperm injections really are, how they work, and why I believe they deliver exceptional results, particularly for the under-eye area.
What Are Salmon Sperm Injections?
Salmon sperm injections is a non-medical term for polynucleotide injections, a regenerative injectable treatment derived from highly purified DNA fragments extracted from salmon.
- They are biocompatible with human skin
- They do not add volume like dermal fillers
- They work by repairing and improving skin quality at a cellular level
In clinic, this treatment is correctly referred to as
polynucleotide injections.
Why Polynucleotides Work So Well Under the Eyes
The under-eye area is one of the most challenging areas to treat in aesthetics:
- The skin is extremely thin
- There is little structural support
- Traditional fillers can look heavy or unnatural
- Some treatments can worsen puffiness
This is exactly why I chose to have polynucleotide injections under my eyes.
Learn more about dedicated under-eye treatments.
My Personal Experience: 5 Years of Under-Eye Polynucleotides
I first had this treatment over five years ago during the initial polynucleotide training in Northern Ireland, delivered by ChromaPhilArt (now PolyPhil). At the time, I already had a strong grounding in regenerative medicine through my Master’s degree in Aesthetic Medicine at Queen Mary University, London, so the science immediately resonated.
My Under-Eye Concerns
- Crepey skin
- Fine lines and texture
- Dark circles
- Early signs of ageing
What I Noticed
- Brighter, fresher under-eye appearance
- Deep hydration of crepey skin
- Softer fine lines and improved texture
- A noticeable confidence boost
What surprised me most was how quickly the area settled — and how many people commented on how refreshed I looked.
How Polynucleotide Injections Work
Polynucleotides stimulate the skin’s own repair processes by:
- Activating fibroblasts
- Supporting collagen and elastin production
- Improving microcirculation
- Reducing inflammation
- Deeply hydrating fragile skin
This makes them particularly effective for ageing or thinning skin, inflammatory skin conditions, and post-procedure healing (including after blepharoplasty).
Does the Treatment Hurt? What Is the Downtime?
- Pain: Very mild (comparable to Botox)
- Downtime: The remainder of the day
- Recovery: Quick and predictable
Most patients return to normal activities the following day.
Who Should Consider Salmon Sperm (Polynucleotide) Injections?
This treatment is suitable for:
- Any age — ideal for collagen banking early
- Perimenopausal and menopausal skin
- All skin types
- Patients with inflammation or delicate skin
- Post-blepharoplasty recovery
I regularly recommend this treatment because it is safe, subtle, and delivers genuine skin quality improvement.
Frequently Asked Questions
What are salmon sperm injections?
Salmon sperm injections are polynucleotide injections made from purified salmon DNA that improve skin quality by stimulating repair and collagen support, particularly in delicate areas like the under eyes.
Are salmon sperm injections fillers?
No. They do not add volume — they improve hydration, texture, and overall skin quality.
Are polynucleotide injections safe?
Yes, when performed by a trained medical professional using reputable products and appropriate technique.
How long do results last?
Results build gradually and typically last several months, with maintenance recommended depending on skin goals and lifestyle.
Are they good for under-eye wrinkles?
Yes — they can be particularly helpful for crepey skin, fine lines, and dullness, where heavier treatments may be less suitable.
Local Expertise in Hillsborough, Lisburn & Belfast
Experience matters — particularly when treating delicate areas such as the under eyes.
You can learn more about my background here:
About Dr Janice Brown.
If you’re considering polynucleotide injections and want a treatment plan tailored to your skin:
Final Thoughts
Salmon sperm injections are not a trend. They are a scientifically grounded, regenerative treatment that delivers natural, refined results — particularly in areas where other injectables struggle. For under-eye rejuvenation, they remain one of my most trusted treatments both clinically and personally.
Medical note: This article is for education and does not replace a medical consultation. Suitability depends on individual anatomy, medical history, and assessment.









